def bit_not_op(v,bit_size):    bit16_not_val = 0    for i in range(0,bit_size):        if ((v >> i)&0x1) == 0 :            bit16_not_val |= (1 << i)    return (bit16_not_val)

# 有符号的16位整数

v_offset = ((v1 << 8) | (v0 << 0))

hight_bit = (v_offset >> 15) & 1

if hight_bit :

   v_offset = bit_not_op(v_offset,16)

   v_offset = v_offset + 1

   v_offset = - (v_offset & 0x7FFF)